Review Article

Critical Roles of Balanced Innate Lymphoid Cell Subsets in Intestinal Homeostasis, Chronic Inflammation, and Cancer

Table 1

Characteristics of intestinal innate lymphoid cells (ILCs).

NKsILC1sILC2sILC3sILCregs

Transcription factorsT-betT-betGATA3, RORαRORγtId3
Active factorsTGF-β, GM-CSFIL-15IL-25, IL-33, TSLPIL-23TGF-β
Effective factorsIFN-γ, IL-22, VEGF, CXCL8IFN-γ, TNF-αIL-5, IL-13IL-22, IL-17, GM-CSF, IFN-γIL-10