Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis

Figure 6

Hydrogen peroxide (H₂O₂) production by neutrophils (PMN) treated or not with IFN-γ (a), TNF-α (b), and GM-CSF (c) for 18 hours in the presence or absence of the anti-Dectin-1 monoclonal antibody (AD) and challenged or not with Pb265 for 4 hours. Box-and-whisker plot showing data distribution of 8 healthy volunteer donors. Statistical significance between groups is indicated.

(a)

(b)

(c)