Elevated Serum IgG Levels Positively Correlated with IL-27 May Indicate Poor Outcome in Patients with HBV-Related Acute-On-Chronic Liver Failure

Figure 1

IgG, IgA, and IgM levels were significantly higher in HBV-ACLF patients independently of HBeAg presence. Pooled data indicated the levels of IgG, IgA, and IgM in each group, where the lines indicated the mean or median. (a) Serum IgG, IgA, and IgM levels were significantly higher in HBV-ACLF patients than in the CHB group and the NC group. No significant differences existed between patients with HBeAg positive and those with HBeAg negative, neither in the CHB group (b) nor in the HBV-ACLF group (c). ACLF: acute-on-chronic liver failure; CHB: chronic hepatitis B; NC: normal control; HBeAg-P: HBeAg-positive; HBeAg-N: HBeAg-negative; ; ; ; ns: not significant.

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(b)

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