Enhancement of the Soluble Form of OX40 and OX40L Costimulatory Molecules but Reduction of the Membrane Form in Type 1 Diabetes (T1D)

Table 3

Correlation between clinical features and soluble levels of OX40 and OX40L.

	sOX40		sOX40L
	Ketosis	0.2191	0.7217	-0.0344	0.8395
GAD	0.0289	0.3379	0.0840	0.4954
ICA	0.0070	0.7302	0.1846	0.1318
IAA	0.0607	0.7442	0.1463	0.2337
DKA	0.0962	0.6942	-0.0107	0.9448
HDL	0.1826	0.1159	-0.0511	0.6630
LDL	0.0733	0.7493	0.1849	0.1123
TC	0.0229	0.9884	0.1528	0.1846
TG	-0.0635	0.1745	0.0131	0.9094
ALT	-0.2506	0.7772	-0.1072	0.3632
AST	-0.1859	0.6487	-0.1434	0.2228
LDH	-0.2732	0.6829	-0.0224	0.8851
GGT	-0.0967	0.7239	-0.142	0.3253
Cr	-0.0148	0.5676	-0.1343	0.2443
BUN	-0.1330	0.1402	-0.0909	0.4317
UA	0.3376	0.0189	-0.1127	0.3323
GLU	0.1428	0.3729	0.0974	0.4627
C0	0.0398	0.4693	0.1008	0.3736
C120	0.2641	0.4974	0.1211	0.4952
HbA1c	0.3045	0.0616	0.3131	0.0001
CD4^+OX40^+ T	-0.3373	0.0225	—	—
CD8^+OX40^+ T	-0.4733	0.7018	—	—
CD3^+OX40^+ T	-0.3629	0.0162	—	—
CD19^+OX40L^+ B	—	—	0.2351	0.0683
CD14^+OX40L^+ monocyte	—	—	0.2499	0.0521
IL-2	0.2461	0.1137	0.3676	0.0252
IL-4	0.1455	0.1232	0.2422	0.1487
IL-6	0.0214	0.0196	0.3139	0.0485
IL-10	-0.1077	0.1482	0.3455	0.0362
TNF-α	0.4713	0.0569	0.1964	0.2448
IFN-γ	0.4238	0.0922	0.5201	0.0056
IL-17a	0.4947	0.0535	0.2291	0.1726