Research Article
IL-21 Expands HIV-1-Specific CD8+ T Memory Stem Cells to Suppress HIV-1 Replication In Vitro
Figure 2
Associations between epitope-specific CD8+ T memory stem cells and CD4+ T cell counts in the peripheral blood of HIV-1-infected individuals. (a–c) The association between CD4+ T cell counts and absolute counts of HIV-1-specific CD8+ T memory stem cells (TSCMs) in 20 combined antiretroviral therapy- (cART-) treated HIV-1-infected individuals. Spearman’s rank correlation coefficients are shown. (d–f) Associations between CD4+ T cell counts and the proportions of interferon gamma- (IFN-γ-) secreting HIV-1-specific CD8+ TSCMs from cART-treated HIV-1-infected individuals. Spearman’s rank correlation coefficients are shown.
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