Research Article

Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice

Figure 4

Liver concentrations of pro- and anti-inflammatory cytokines during early infection by LPF. A/J C5+/+ and A/J C5-/- mice were inoculated i/p with LPF or PBS and then euthanized on the third or the sixth days. The concentrations of several cytokines were analyzed in the liver extracts by ELISA, using the same protein concentration in each sample. Significant differences are indicated as when . dpi: days postinfection.
(a)
(b)
(c)
(d)
(e)
(f)