Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice

Table 2

Serum cytokine levels in A/J mouse strain infected by LPF.

		A/J C5^+/+			A/J C5^-/-
	PBS ()	3 dpi ()	6 dpi ()	PBS ()	3 dpi ()	6 dpi ()
TNF-α; (pg/ml)		^a	^b		^a	^b
IFN-γ; (pg/ml)	un
IL-6; (pg/ml)	un			un
MCP-1; (pg/ml)	un		un	un		un

The concentrations of cytokines were analyzed in the serum of infected mice by flow cytometry (CBA). Abbreviations: A/J C5^+/+ (A/J C5-sufficient mice), A/J C5^-/- (A/J C5-deficient mice), dpi: days postinfection; un: undetected. Statistical representation: a vs. PBS; b vs. 3 dpi. All data are presented as mean and standard error.