Figure 2: Modification of lung immune contexture induced by CRM aerosolization. Bars () and representative dot plots of the percentage of AMs (identified as CD45+/FL-1+CD11c+ cells) and of CD103+ DCs (identified as CD45+/CD11b-/CD103+CD11c+ cells) evaluated in lung suspensions of 4 mice/group injected with B16 melanoma cells and aerosolized with saline or combined CRMs (a). of IL10, IL12, STAT1, STAT6, TNF-α, IFNγ, and IL-8 mRNA levels, evaluated by real-time PCR in adherent cell fraction of digested lungs (4-8 mice/group) (b). Results are presented as 2-ΔCt. by Student’s -test.