Figure 3: Effects of CRM aerosolization on the recruitment and activation of lung antitumor effector cells. Bars () and representative dot plots of the percentage of NK cells (identified as CD45+/CD3-/CD49b+ cells) and T cells (identified as CD45+/CD3+ cells) (a) and of CD69 expressing NK and T cells (b) evaluated in 4 mice/group injected with B16 melanoma cells and aerosolized with saline or combined CRMs. Bars () represent the percentage of the specific lysis of B16 target cells cultured for 4 h with nonadherent cells obtained from the lung suspensions of 4 mice/group (c). , by Student’s -test.