Research Article
Sjögren’s Syndrome: Concerted Triggering of Sicca Conditions
Table 1
Clinical and serological characteristics of study patients.
| | Patient group features | pSS () | RA () | sSS () | nSS () |
| | Age in years, mean (range) | 57 (49–78) | 54 (50–78) | 59 (49–70) | 59 (49–91) | | Disease duration in years, mean ± SD | 8 ± 5 | 10 ± 9 | 16 ± 10 | 8 ± 7 | | DAS28, mean ± SD | — | 5.41 ± 1.43 | 5.59 ± 1.55 | — | | Duration of dryness in years, mean ± SD | 6 ± 4 | 0 | 6 ± 5 | 6 ± 7 | | Schirmer’s I test positive (≤5 mm/5 min), n (%) | 26 (86.6) | 0 (0) | 23 (72) | 6 (18) | | Unstimulated salivary flow positive (≤1.5 mL/15 min), n (%) | 25 (83.3) | 0 (0) | 13 (40.7) | 2 (6) | | Unstimulated salivary flow (mL/15 min), mean ± SD | 1.36 ± 0.95 | 3.45 ± 1.36 | 1.80 ± 1.25 | 2.88 ± 1.44 | | Focus score positive (number of lymphocytic foci/4 mm2), n (%) | 29 (100) | 0 | 32 (100) | 0 (0) | | Positive autoantibodies | | | | | | RF, n (%) | 14 (48.2) | 20 (62.5) | 23 (71.9) | — | | ACCP, n (%) | 1 (3.4) | 24 (75) | 16 (50) | — | | ANA, n (%) | 21 (72.4) | 1 (3.1) | 7 (21.8) | — | | Anti-SSA+, n (%) | 4 (13.8) | 0 (0) | 2 (2.25) | — | | Anti-SSB+, n (%) | 0 (0) | 0 (0)– | 0 (0) | — | | Anti-SSA/SSB+, n (%) | 18 (62.1) | 0 (0) | 3 (9.3) | — |
|
|
