Association of Melatonin Pathway Gene’s Single-Nucleotide Polymorphisms with Systemic Lupus Erythematosus in a Chinese Population
Table 1
Demographic characteristics and clinical features of patients with SLE and control subjects.
Parameters
Patients with SLE ()
Healthy controls ()
Demographic characteristics
Age (year)
37.00 (28.00, 46.00)
38.00 (30.00, 47.00)
Female, (%)
438 (88.5)
434 (88.0)
Male, (%)
58 (11.5)
59 (12.0)
Disease duration (year)
4.10 (1.05, 9.06)
NA
BMI (kg/m2)
21.48 (19.72, 23.43)
NA
SLEDAI
11.40 ± 9.07
NA
Disease manifestations
NA
Malar rash, (%)
224 (45.3)
NA
Discoid rash, (%)
94 (19.0)
NA
Photosensitivity, (%)
193 (39.0)
NA
Oral ulcers, (%)
119 (24.0)
NA
Arthritis, (%)
245 (49.5)
NA
Serositis, (%)
45 (9.1)
NA
Renal abnormality, (%)
184 (37.2)
NA
Neurological abnormality, (%)
21 (4.2)
NA
Hematological abnormality, (%)
338 (68.3)
NA
Immunological abnormality, (%)
362 (73.1)
NA
BMI: Body mass index; : number; SLE: systemic lupus erythematosus; SLEDAI: systemic lupus erythematosus disease activity index. Data with normal distribution were described as mean and standard deviation (SD). Data with skewed distribution were described as median and interquartile range (IQR).