Research Article

Association of Melatonin Pathway Gene’s Single-Nucleotide Polymorphisms with Systemic Lupus Erythematosus in a Chinese Population

Table 1

Demographic characteristics and clinical features of patients with SLE and control subjects.

ParametersPatients with SLE ()Healthy controls ()

Demographic characteristics
 Age (year)37.00 (28.00, 46.00)38.00 (30.00, 47.00)
 Female, (%)438 (88.5)434 (88.0)
 Male, (%)58 (11.5)59 (12.0)
 Disease duration (year)4.10 (1.05, 9.06) NA
 BMI (kg/m2)21.48 (19.72, 23.43) NA
 SLEDAI11.40 ± 9.07NA
Disease manifestationsNA
 Malar rash, (%)224 (45.3)NA
 Discoid rash, (%)94 (19.0)NA
 Photosensitivity, (%)193 (39.0)NA
 Oral ulcers, (%)119 (24.0)NA
 Arthritis, (%)245 (49.5)NA
 Serositis, (%)45 (9.1)NA
 Renal abnormality, (%)184 (37.2)NA
 Neurological abnormality, (%)21 (4.2)NA
 Hematological abnormality, (%)338 (68.3)NA
 Immunological abnormality, (%)362 (73.1)NA

BMI: Body mass index; : number; SLE: systemic lupus erythematosus; SLEDAI: systemic lupus erythematosus disease activity index. Data with normal distribution were described as mean and standard deviation (SD). Data with skewed distribution were described as median and interquartile range (IQR).