3β-Acetyloxy-oleanolic Acid Attenuates Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation

Figure 3

AOA can significantly reduce serum dsDNA levels in a mouse model of lupus nephritis. (a, b) Serum from the mice in each group was collected at 2 months old (pristine injection), 6 months old (4 months after pristine injection), 7 months (one month after AOA treatment), and 8 months (two months after AOA treatment—the endpoint of this experiment), and the antibody levels were detected by ELISA. Normal controls (), model controls (), positive drug group-prednisone acetate (), and AOA-treated group (). The data were repeated 3 times with consistent results. Data are presented as . , , and , calculated versus the control group; and calculated versus the model group.

(a)

(b)