High-Titre Neutralizing Antibodies to H1N1 Influenza Virus after Mouse Immunization with Yeast Expressed H1 Antigen: A Promising Influenza Vaccine Candidate

Figure 2

Structural representation of the molecular model of the N-glycosylated H1 monomer (a) and trimer (b). The HA1 domain is depicted with the blue ribbon, the HA2 domain is depicted with the green, and the oligosaccharides are represented by orange atomistic balls. The sugar-bonded asparagines are depicted in atomistic representations, according to their respective domain colours. The models were constructed based on the crystallographic structure of the H1 haemagglutinin (PDB ID code 3LZG, [27]).

(a)

(b)