Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis

Table 2

Innate lymphoid cells in the gut.

Types	Surface marker		Stimulus	Regulatory transcription factor	Signature released cytokines	Functions in the gut barrier
	Mouse	Human
ILC1	CD160	CD103	IL-12, IL-15	T-bet	IFN-γ, TNF-α, GM-CSF, granzyme, perforin	Defense against virus, pathogens
	NKp46	CD160
	NK1.1	CD56
		NKp46
		NKp44
ILC2	IL17RB	IL17RB	IL-25, IL-33, TSLP	GATA3	IL-4, IL-5, IL-13, IL-9, amphiregulin	Helminth expulsion
	IL-33R	IL-33R
	CD25	CD25
	CD127	CD127
		CRTH2
ILC3	NKp46	NKp44	IL-1β, IL-23, NCR ligand	RORγT	IL-17, IL-22, GM-CSF, TNF-α	Defense against bacteria, fungi