Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages

Table 2

Top 10 of microRNAs.

(a)

4 h poststimulus
MTcES vs. M0				MTcES+LPS vs. M0				MLPS vs. M0
Upregulated		Downregulated		Upregulated		Downregulated		Upregulated		Downregulated
MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC
mmu-miR-421-3p	102.60	mmu-miR-539-5p	0.02	mmu-miR-155-5p	676.18	mmu-miR-190b-5p	0.49	mmu-miR-155-5p	402.62	mmu-miR-125a-3p	0.33
mmu-miR-484	2.35	mmu-miR-467c-5p	0.02	mmu-miR-546	112.84	mmu-miR-1955-5p	0.47	mmu-miR-546	76.67	mmu-miR-1224-5p	0.31
mmu-miR-350-3p	2.22	mmu-miR-1193-3p	0.02	mmu-miR-128-3p	88.90	mmu-miR-1933-5p	0.41	mmu-miR-146a-5p	2.09	mmu-miR-467f	0.02
mmu-miR-148b-3p	2.14	mmu-miR-199a-3p	0.01	mmu-miR-421-3p	84.34	mmu-miR-125a-3p	0.36			mmu-miR-539-5p	0.02
mmu-miR-125a-3p	2.13	mmu-miR-383-5p	0.01	mmu-miR-331-3p	74.08	mmu-miR-664-3p	0.35			mmu-miR-380-3p	0.02
mmu-miR-191-5p	2.12	mmu-miR-489-3p	0.01	mmu-miR-484	2.62	mmu-miR-1224-5p	0.35			mmu-miR-467c-5p	0.02
mmu-miR-30b-5p	2.09	mmu-miR-1953	0.01	mmu-miR-191-5p	2.46	mmu-miR-1193-3p	0.02			mmu-miR-714	0.02
mmu-miR-103-3p	2.07	mmu-miR-743a-3p	0.01	mmu-miR-30b-5p	2.44	mmu-miR-2137	0.01			mmu-miR-489-3p	0.01
mmu-miR-29b-3p	1.99	mmu-miR-410-3p	0.01	mmu-miR-99b-5p	2.40	mmu-miR-210-3p	0.01			mmu-miR-2137	0.01
		mmu-miR-1933-5p	0.00	mmu-miR-148b-3p	2.32	mmu-miR-804	0.01			mmu-miR-804	0.01

FC: fold change

(b)

24 h poststimulus
MTcES vs. M0				MTcES+LPS vs. M0				MLPS vs. M0
Upregulated		Downregulated		Upregulated		Downregulated		Upregulated		Downregulated
MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC	MicroRNA	FC
mmu-miR-362-5p	77.49	mmu-miR-743b-5p	0.01	mmu-miR-155-5p	4272.7	mmu-miR-326-3p	0.48	mmu-miR-155-5p	14139.0	mmu-miR-2137	0.01
mmu-miR-421-3p	93.67	mmu-miR-1949	0.01	mmu-miR-210-3p	285.39	mmu-miR-361-5p	0.34	mmu-miR-1933-5p	901.35	mmu-miR-362-3p	0.01
mmu-miR-1929-5p	74.93	mmu-miR-2134	0.01	mmu-miR-674-5p	171.63	mmu-miR-27a-3p	0.32	mmu-miR-210-3p	639.8	mmu-miR-484	0.01
		mmu-miR-2137	0.01	mmu-miR-331-3p	127.7	mmu-miR-221-3p	0.29	mmu-miR-574-3p	579.11	mmu-miR-152-3p	0.01
				mmu-miR-7a-5p	109.76	mmu-miR-23a-3p	0.26	mmu-miR-673-3p	518.4	mmu-miR-714	0.005
				mmu-miR-574-3p	96.8	mmu-miR-27b-3p	0.26	mmu-miR-674-5p	331.59	mmu-miR-107-3p	0.004
				mmu-miR-467a-5p	92.80	mmu-miR-762	0.23	mmu-miR-466a-5p	308.23	mmu-miR-324-5p	0.004
				mmu-miR-1929-5p	88.81	mmu-miR-1224-5p	0.22	mmu-miR-489-3p	284.88	mmu-miR-148b-3p	0.003
				mmu-miR-489-3p	87.81	mmu-miR-199a-3p	0.01	mmu-miR-1900	261.532095	mmu-miR-350-3p	0.002
				mmu-miR-139-5p	83.82	mmu-miR-145-5p	0.01	mmu-miR-1953	242.8512311	mmu-miR-762	0.001

FC: fold change.