Curcumin and α/β-Adrenergic Antagonists Cotreatment Reverse Liver Cirrhosis in Hamsters: Participation of Nrf-2 and NF-κB

Figure 4

Detection of NF-κB and Nrf2 in liver tissue slides by immunohistochemistry: intact, cirrhotic, placebo, doxazosin (D), doxazosin more curcumin (D+Cu), carvedilol (Ca), carvedilol more curcumin (Ca+Cu), doxazosin more carvedilol (D+Ca), doxazosin more carvedilol more curcumin (D+Ca+Cu), and finally curcumin (Cu). Positive cells to NF-κB and Nrf2 are indicated by arrows (×400).