Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum

Figure 1

Serological markers (LAM and PGL-I) and TLR 1 and 2 in the peripheral blood of leprosy reaction and reaction-free leprosy patients. (a) Comparison between mean levels of anti-LAM IgG by ELISA (Enzyme-Linked Immunosorbent Assay) in the leprosy reaction and reaction-free leprosy patients. (b) Comparison between mean levels of anti-PGL-I IgM by ELISA in the leprosy reaction and reaction-free leprosy patients. (c) Comparison between mean levels of anti-LAM IgG by ELISA in the reactional and reaction-free leprosy patients PB and MB. (d) Comparison between mean levels of anti-PGL-I IgM by ELISA in the reactional and reaction-free leprosy patients PB and MB. (e) Comparison between TLR1 and TLR2 mRNA gene expression in the T1R, ENL, reaction-free leprosy patients PB and MB. The RNA expression was represented in fold change in relation to the endogenous control.

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