Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum

Table 1

Clinical and epidemiological variables of reactional and reaction-free leprosy patients.

		I/TT				BT (PB)				BT(MB)				BB				BL				LL				Total of groups				Total
		Leprosy reaction		Reaction-free		Leprosy reaction		Reaction-free		Leprosy reaction		Reaction-free		Leprosy reaction		Reaction-free		Leprosy reaction		Reaction-free		Leprosy reaction		Reaction-fee		Leprosy reaction		Reaction-free
			%	°	%		%		%		%		%		%		%		%		%		%		%		%		%		%
Operational classification	PB	0	0	6	100	0	0	2	100	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	47	8	23.6
	MB	0	0	0	0	0	0	0	0	1	20	4	80	4	80	1	20	3	60	2	40	9	81.8	2	18	17	100	9	53	23	67.6
Leprosy reaction	T1R									1	5.9			4	23.5			2	11.8			0	0			7	41.2			7	20.5
	ENL									0	0			0	0			1	5.9			9	53			10	58.8			10	29.4
Period of occurrence of leprosy reaction	Before treatment									1	5.9			3	17.6			1	5.9			0	0			5	29.4			5	14.7
	During treatment									0	0			0	0			0	0			0	0			0	0			0	0
	After treatment									0	0			1	5.9			2	11.8			9	53			12	70.6			12	35.2
Disability grade	0	0	0	6	100	0	0	2	100	1	20	3	60	1	20	0	0	1	20	2	40	5	46	0	0	8	23.5	13	38.2	21	61.7
	1	0	0	0	0	0	0	0	0	0	0	1	20	1	20	1	20	1	20	0	0	3	27	2	18	5	14.7	4	11.8	9	26.4
	2	0	0	0	0	0	0	0	0	0	0	0	0	2	40	0	0	1	20	0	0	1	9	0	0	4	11.8	0	0	4	11.7
Sex	Male	0	0	0	0	0	0	2	100	1	20	4	80	2	40	1	20	2	40	2	40	5	45.5	1	9.1	10	58.8	10	58.8	20	58.8
	Female	0	0	6	100	0	0	0	0	0	0	0	0	2	40	0	0	1	20	0	0	4	36.3	1	9.1	7	41.2	7	41.2	14	41.2
Age group	18-24	0	0	0	0	0	0	0	0	0	0	0	0	1	20	0	0	0	0	0	0	0	0	0	0	1	2.9	0	0.0	1	2.9
	25-34	0	0	2	33	0	0	0	0	0	0	1	20	1	20	0	0	0	0	0	0	1	9.09	0	0	2	5.9	3	8.8	5	14.7
	35-44	0	0	3	50	0	0	0	0	0	0	0	0	1	20	1	20	2	40	0	0	2	19	1	9	5	14.7	5	14.7	10	29.4
	45-54	0	0	0	0	0	0	1	50	0	0	1	20	1	20	0	0	0	0	1	20	3	27.3	1	9	4	11.8	4	11.8	8	23.6
	55-64	0	0	1	17	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	27.3	0	0	3	8.8	1	2.9	4	11.7
	≥65	0	0	0	0	0	0	1	50	1	20	2	40	0	0	0	0	1	20	1	20	0	0	0	0	2	5.9	4	11.8	6	17.7
	Total	0	0	6	35.2	0	0	2	11.8	1	5.9	4	23.5	4	23.5	1	5.9	3	17.6	2	11.8	9	53	2	11.8	17	50	17	50	34	100

I: indeterminate leprosy; TT: tuberculoid leprosy; BT: borderline tuberculoid; BB: borderline borderline; BL: borderline lepromatous; LL: lepromatous leprosy; PB: paucibacillary; MB: multibacillary;