Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum

Table 2

Correlation matrix among dependent and independent variables of the leprosy reaction cases, based on Pearson’s correlation.

Variables	Leprosy reaction
	IL-10			Toll-like receptor 2
		CI (95%)	value		CI (95%)	value
Number of injured nerves	0.62	0.13–0.87	0.018	0.47	-0.08–0.80	0.087
Number of skin lesions	0.69	0.26–0.90	0.005	0.69	0.26–0.90	0.005
DG	0.28	0.29–0.71	0.331	0.13	-0.42–0.62	0.639
Age	-0.36	-0.75–0.20	0.193	-0.30	-0.72–0.27	0.282
Toll-like receptor 1	0.43	-0.13–0.78	0.121	0.44	-0.11–0.79	0.109
Toll-like receptor 2	0.89	0.68–0.96	<0.001
IL-10				0.89	0.68–0.96	<0.001
IFN-γ	0.05	-0.54–0.61	0.877	0.37	0.52–0.94	0.233
IL-4	-0.17	-0.64–0.40	0.561	0.09	-0.46–0.60	0.747
TNF-α	-0.031	-0.55–0.51	0.916	-0.15	-0.63–0.41	0.605
Anti-LAM	0.55	0.03–0.84	0.043	0.70	0.29–0.90	0.004
Anti-PGL-I	0.70	0.08–0.85	0.004	0.68	0.14–0.87	0.007
Bacterial index	0.21	-0.36–0.67	0.468	0.20	-0.36–0.66	0.478

: Pearson’s correlation coefficient; CI (95%): confidence interval of 95%, DG: disability grade; IL-10: interleukin 10; IFN-γ: interferon gamma; IL-4: interleukin 4; TNF-α: tumor necrosis factor (alpha); anti-LAM: anti-lipoarabinomannan antibody; anti-PGL-I: anti-phenolic glycolipid-I antibody. Diagnostic data.