PM2.5 Exposure in the Respiratory System Induces Distinct Inflammatory Signaling in the Lung and the Liver of Mice

Figure 2

Leukocytes in hematoxylin and eosin- (H&E-) stained tissue sections and transmission electron microscopy (TEM) images after PM2.5 exposure. (a, b) The histopathological structures of lung and liver tissues were confirmed by H&E staining after PM2.5 treatment. In the PM2.5-treated group, lymphocytes were observed in both organs. Scale bar, 20 μm. (c) TEM images of the lung revealed that the number of lymphocytes in the alveolar sacs after PM2.5 treatment increased. (d) Liver imaging showed the formation of lymphocyte clusters and indicated that an inflammatory reaction had occurred. An eosinophil was also observed (white box). Black arrows indicate lymphocytes in the bottom panels of (c) and (d). Scale bar, 10 μm.

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