Research Article
Modifying Graft-versus-Host Disease in a Humanized Mouse Model by Targeting Macrophages or B-Cells
Figure 2
Survival and comparison of fraction reconstituted huPBMCs in B-cell depletion. (a) The difference in percentage of huPBMCs in mice either treated with Rituximab to induce B-cell depletion or not treated with Rituximab, and (b) a comparison of the survival portions between the RAG2 -/-γc-/- mice with and without Rituximab treatment versus control mice (), consisting of 5 RAG2 -/-γc-/- mice with Rituximab but no huPBMCs and 5 RAG2 -/-γc-/- control mice (with no Rituximab nor huPBMCs).
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