Cross-Disease Innate Gene Signature: Emerging Diversity and Abundance in RA Comparing to SLE and SSc

Table 3

Association rules identified for (a) RA, (b) SLE, and (c) SSc.

No.	Rule	Support	Confidence	Number of patients identified
(a) RA
1	TLR3 high & IL1RAP high	0.13	1.00	11
2	TLR3 high & TLR10 high	0.12	1.00	10
3	TLR3 high & TLR9 low	0.12	1.00	10
4	TLR4 low & TLR8 high & IL1RAP high	0.14	1.00	12
5	TLR5 high & IL18 high & IL18R1 low	0.14	1.00	12
6	TLR6 low & IL1R1 high & SIGIRR high & CXCL8 low	0.12	0.91	10
(b) SLE
1	TLR5 low & TLR6 high & IL1RN low & IL18R1 low	0.10	0.90	9
2	TLR1 low & TLR8 low & IL1R1 low & IL1RN low & IL18 low & IL18R1 low	0.13	0.85	11
3	TLR3 low & IL1B high	0.10	0.82	9
(c) SSc
1	TLR5 low & IL1RN high & IL18R1 low	0.10	1.00	9
2	TLR5 low & TLR3 low & IL18 high	0.10	0.82	9
3	TLR5 low & IL1R1 high & IL18R1 low	0.10	0.75	9

The data set for each gene was divided into low/high expression by means of a particular gene expression of the whole data set.