Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro

Figure 3

Reduction of TNF-α production in HepG2 cells and THP-1 cells. In this coculture study, the apical side HepG2 cells were stimulated with heat-killed LABs for 48 h, after which the basolateral THP-1 cells were treated with LPS for 12 h. The protein levels of TNF-α in both apical and basolateral sides were determined. Cell treated with LPS was used as control. Different superscript letters indicate significant differences at the 0.05 level.