Research Article
High-Risk Indicators of Renal Involvement in Primary Sjogren’s Syndrome: A Clinical Study of 1002 Cases
Table 1
Demographic, clinical, histological, immunological, and inflammatory features of primary Sjogren’s syndrome with or without renal involvement.
| | Without renal involvement 840 | With renal involvement 162 | value |
| Seroperitoneum | 0 | 6 (3.7%) | 0.000 | Dizziness | 12 (1.4%) | 8 (4.9%) | 0.003 | Palpitate | 14 (1.7%) | 6 (3.7%) | 0.090 | Breathe hard | 26 (3.1%) | 9 (5.6%) | 0.118 | Digestive tract symptoms | 19 (2.3%) | 31 (19.1%) | 0.000 | Respiratory system symptoms | 30 (3.6%) | 15 (9.3%) | 0.001 | Congestion of throat | 1 (0.1%) | 10 (6.2%) | 0.000 | Bilateral pleural effusion | 0 | 3 (1.9%) | 0.000 | Lipsotrichia | 53 (6.3%) | 4 (2.5%) | 0.053 | Dry cough | 4 (0.5%) | 1 (0.6%) | 0.815 | Edema in the face | 5 (0.6%) | 14 (8.6%) | 0.000 | Edema of both lower limbs | 13 (1.5%) | 42 (25.9%) | 0.000 | Hypourocrinia | 0 | 4 (2.5%) | 0.000 | Frequent micturition | 8 (1.0%) | 10 (6.2%) | 0.000 | Urgency of urine | 8 (1.0%) | 7 (4.3%) | 0.000 | Odynuria | 3 (0.4%) | 4 (2.5%) | 0.003 | Rampant caries | 187 (22.3%) | 34 (21%) | 0.720 | Erythema | 149 (17.7%) | 23 (14.2%) | 0.274 | Weak | 119 (14.2%) | 50 (30.9%) | 0.000 | Poor appetite | 9 (1.0%) | 25 (15.4%) | 0.000 | Dry mouth | 669 (79.6%) | 129 (79.6%) | 0.997 | Xerophthalmia | 457 (54.4%) | 94 (58%) | 0.396 | Arthralgia | 493 (58.7%) | 68 (42%) | 0.000 | Fever | 149 (17.7%) | 28 (17.3%) | 0.890 | Reynolds | 33 (3.9%) | 9 (5.6%) | 0.344 | Dental ulcer | 69 (8.2%) | 16 (9.9%) | 0.487 | Courpature | 1 (0.1%) | 1 (0.6%) | 0.193 | Hematuria | 0 | 1 (0.6%) | 0.023 | Polydipsia | 1 (0.1%) | 2 (1.2%) | 0.021 | Diuresis | 1 (0.1%) | 2 (1.2%) | 0.021 | Nocturia | 2 (0.2%) | 17 (18.5%) | 0.000 | Parotid swelling and pain | 29 (3.5%) | 3 (1.9%) | 0.289 | Anti-scl-70 | 0 | 2 (1.2%) | 0.001 | Anti-Jo-1 | 0 | 2 (1.2%) | 0.001 | pANCA | 17 (2%) | 4 (2.5%) | 0.717 | cANCA | 3 (0.4%) | 1 (0.6%) | 0.631 | RF | 144 (17.1%) | 44 (27.2%) | 0.003 | Anti-ENA | 169 (20.1%) | 59 (36.4%) | 0.000 | Anti-ds DNA | 18 (2.1%) | 3 (1.9%) | 0.813 | Anti-SSA | 579 (68.9%) | 80 (49.4%) | 0.000 | Anti-SSB | 54 (6.4%) | 19 (11.7%) | 0.017 | Anti-Sm | 4 (0.5%) | 4 (2.5%) | 0.009 | Anti-RNP | 87 (10.4%) | 15 (9.3%) | 0.672 |
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