Enhancement of Macrophage Function by the Antimicrobial Peptide Sublancin Protects Mice from Methicillin-Resistant Staphylococcus aureus

Figure 3

Analysis of p38, ERK, and JNK signaling pathways in RAW264.7 cells treated with sublancin for different times. RAW264.7 cells were treated with 100 μM sublancin for the indicated times, and the phosphorylation of p38, ERK1/2, and JNK were detected by Western blot analysis. Representative immunoblots and quantitation of the phosphorylation abundance of p38 (a), ERK1/2 (b), and JNK (c). The values are presented as (). Significant differences with control cells were designated as , , or .

(a)

(b)

(c)