Research Article

Similar Transition Processes in Synovial Fibroblasts from Rheumatoid Arthritis and Osteoarthritis: A Single-Cell Study

Figure 2

Clustering and developmental trajectory of RA and OA synovial fibroblasts. (a) -SNE visualization of SFs from RA and OA patients. OA SFs: red; RA SFs: blue. (b) Developmental trajectory constructed by the R package Monocle. Different colors represent different states recognized by Monocle. (c) Distribution of SFs’ origin in the developmental trajectory. SFs from OA (red) and SFs from RA (blue) show similar distribution patterns.
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