MTOR-Mediated Autophagy Is Involved in the Protective Effect of Ketamine on Allergic Airway Inflammation

Figure 1

Individual mice were sensitized by intraperitoneal injection with ovalbumin (OVA) or saline on days 0 and 7, then challenged for 30 min per day with 1% aerosolized OVA or saline on days 14–21. One hour before aerosol OVA challenge, mice were injected intraperitoneally with 25, 50, and 100 mg/kg ketamine or equivalent saline.