Detection by Flow Cytometry of Anti-DNA Autoantibodies and Circulating DNA Immune Complexes in Lupus Erythematosus

Table 2

Anti-DNA antibodies in patients with lupus nephritis or incomplete lupus erythematosus or drug-induced lupus.

Patients	Nb of positive sera (%)
	usCLIFT positive	EliA™-dsDNA		FCM test
				IC-ctDNA	IC-eDNA
Lupus nephritis
	4 (44%)	6 (67%)	3 (33%)	2 (22%)	4 (44%)
Chronic CL^
	3 (21%)	6 (43%)	2 (14%)	5 (36%)	3 (21%)
Subacute CL^&
	2 (33%)	3 (50%)	2 (33%)	3 (50%)	2 (33%)
DIL^§
	1 (33%)	3 (100%)	0 (0%)	2 (66%)	1 (33%)

Patients with <4 ACR criteria, but those with anti-DNA antibodies satisfied SLICC criteria for SLE [2, 22, 23]. ^Chronic cutaneous lupus. ^&Five patients out of 6 with subacute cutaneous lupus had anti-Ro60 antibodies. ^§Drug-induced lupus; 2 patients were treated by infliximab, and another one by anticancer chemotherapy.