A Single 48 mg Sucralose Sip Unbalances Monocyte Subpopulations and Stimulates Insulin Secretion in Healthy Young Adults

Table 1

Demographic, metabolic, and hematic characteristics of the study population.

Parameters	Placebo	Sucralose	value
Gender (W/M)	8/12	8/17	0.288
Age (years)			0.158
BMI (kg/m^2)			0.177
Waist circumference (cm)			0.074
SBP (mmHg)			0.225
DBP (mmHg)			0.419
Blood glucose (mg/dL)			0.172
HbA1c (%)			0.497
Serum insulin (μU/L)			0.335
HOMA-IR (a.u.)			0.298
Total cholesterol (mg/dL)			0.418
LDL (mg/dL)			0.393
HDL (mg/dL)			0.349
Triglycerides (mg/dL)			0.392
BUN (mg/dL)			0.249
Serum creatinine (mg/dL)			0.165
Hematocrit (%)			0.097
Total leukocytes (10^3/μL)			0.187
Monocytes (10^3/μL)			0.109
Monocytes (%)			0.134

Data are expressed as deviation. The Shapiro-Wilk test was used to estimate normality in data distribution. Significant differences were estimated by means of performing the Student -test with the exception of women/men proportion that was estimated by means of the chi-squared test. Differences were considered significant when . Abbreviations: W: women; M: men; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: glycated hemoglobin; HOMA-IR: homeostatic model assessment of insulin resistance; LDL: low-density lipoprotein; HDL: high-density lipoprotein; BUN: blood urea nitrogen; a.u.: arbitrary units.