Journal of Immunology Research / 2019 / Article / Tab 4

Research Article

The Role of TLR4 Asp299Gly and TLR4 Thr399Ile Polymorphisms in the Pathogenesis of Urinary Tract Infections: First Evaluation in Infants and Children of Greek Origin

Table 4

The distribution of TLR4 Asp299Gly and Thr399Ile polymorphisms in patients and controls.

PatientsControls
Frequency (%)
Group A ()Group A1 ()Group A2 ()Group C ()

TLR4 Asp299GlyGenotype
AA37 (72.5)25 (71.4)12 (75.0)98 (89.9)
AG14 (27.5)10 (28.6)4 (25.0)9 (8.26)
GG0 (0.00)0 (0.00)0 (0.00)2 (1.84)
0.02446
Allele
A88 (0.86)60 (0.86)28 (0.88)205 (0.94)
G14 (0.14)10 (0.14)4 (0.12)13 (0.06)
0.06361
TLR4 Thr399IleGenotype
CC50 (98.04)34 (97.1)16 (100)96 (88.07)
CT1 (1.96)1 (2.9)0 (0.00)12 (11.01)
TT0 (0.00)0 (0.00)0 (0.00)1 (0.92)
0.3465
Allele
C101 (0.99)69 (0.99)32 (1)(0.94)
T1 (0.01)1 (0.01)0 (0.00)(0.06)
0.542

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