The Role of TLR4 Asp299Gly and TLR4 Thr399Ile Polymorphisms in the Pathogenesis of Urinary Tract Infections: First Evaluation in Infants and Children of Greek Origin

Table 4

The distribution of TLR4 Asp299Gly and Thr399Ile polymorphisms in patients and controls.

	Patients		Controls
Frequency (%)
	Group A ()	Group A1 ()	Group A2 ()	Group C ()
TLR4 Asp299Gly	Genotype
AA	37 (72.5)	25 (71.4)	12 (75.0)	98 (89.9)
AG	14 (27.5)	10 (28.6)	4 (25.0)	9 (8.26)
GG	0 (0.00)	0 (0.00)	0 (0.00)	2 (1.84)
		0.02446
Allele
A	88 (0.86)	60 (0.86)	28 (0.88)	205 (0.94)
G	14 (0.14)	10 (0.14)	4 (0.12)	13 (0.06)
		0.06361
TLR4 Thr399Ile	Genotype
CC	50 (98.04)	34 (97.1)	16 (100)	96 (88.07)
CT	1 (1.96)	1 (2.9)	0 (0.00)	12 (11.01)
TT	0 (0.00)	0 (0.00)	0 (0.00)	1 (0.92)
		0.3465
Allele
C	101 (0.99)	69 (0.99)	32 (1)	(0.94)
T	1 (0.01)	1 (0.01)	0 (0.00)	(0.06)
	0.542