Research Article

Sm16, A Schistosoma mansoni Immunomodulatory Protein, Fails to Elicit a Protective Immune Response and Does Not Have an Essential Role in Parasite Survival in the Definitive Host

Table 1

Endpoint titers of specific IgG antibodies against rSm16 in immunized mice.

1st dose2nd dose3rd dose
IgGIgG1IgG2aIgGIgG1IgG2aIgGIgG1IgG2a

rSm16/Freund’s6,4001,60020051,20025,6001,600204,800102,4003,200
rSm16/alum25,60012,800200102,400102,4003,200408,600204,8003,200