CD38 Deficiency Downregulates the Onset and Pathogenesis of Collagen-Induced Arthritis through the NF-κB Pathway

Figure 2

Inhibition of allogeneic stimulatory function of BMDCs generated over 7 days from CD38^-/- mice. DCs cultured from the bone marrow of the WT and CD38^-/- mice (/group, DCs in each group were combined and distributed into 3 wells independently) were used as stimulator cells and incubated with allogeneic T cells from BALB/c mice for 3 days in an MLR. T cell proliferation was detected by CCK-8 assay. The data presented one of three independent experiments (, ).