Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations

<div>Correlations between lung function (expressed as FEV1% predicted) and mRNA expression of MMP-12, NE, and TIMP-4 in PBMCs and concentration of MMP-12 in serum from patients with COPD. (a) Correlation between FEV1 and expression of mRNA for MMP-12 in PBMCs. (b) Correlation between FEV1 and expression of mRNA for NE in PBMCs. (c) Correlation between FEV1 and expression of mRNA for TIMP-4 in PBMCs. (d) Correlation between FEV1 and concentration of MMP-12 in serum. Abbreviations: FEV1s, forced expiratory volume in 1 second.</div>

Journal of Immunology Research

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Figure 7

Figure 7: Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations 

Figure 7 | Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations 