Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus

Table 1

Characteristics of 130 SLE patients and 55 healthy controls.

	SLE	Control
Age			0.230	0.818
Gender (F : M)	120 : 10	49 : 6	0.506	0.477
WBC	5.300 (3.638, 7.710)	—	—	—
HB		—	—	—
PLT	162.0 (115.0, 237.5)	—	—	—
D-dimer	248.0 (106.0, 658.0)	—	—	—
IgG	15.90 (11.55, 19.85)	—	—	—
IgA	2.480 (1.770, 3.860)	—	—	—
IgM	0.9710 (0.634, 1.415)	—	—	—
C3	0.5970 (0.427, 0.840)	—	—	—
C4	0.1230 (0.062, 0.184)	—	—	—
ESR	30.00 (17.00, 56.00)	—	—	—
RF	30 (23.62%)	—	—	—
CRP	4.750 (1.903, 12.28)	—	—	—
CK	28.50 (18.25, 45.75)	—	—	—
Cr	53.00 (45.00, 66.00)	—	—	—
Anti-dsDNA	46.65 (10.20, 182.3)	—	—	—
AnuA	33.76 (6.948, 164.5)	—	—	—
Anti-SSA	53.91%	—	—	—
Anti-SSB	11.72%	—	—	—
Anti-RNP	49.61%	—	—	—
	71.09%	—	—	—
SLEDAI-	64.62%	—	—	—

F: female; M: male; WBC: white blood cell; HB: hemoglobin; PLT: platelet count; IgG: immunoglobulin G; IgA: immunoglobulin A; IgM: immunoglobulin M; C3: complement component 3; C4: complement component 4; ESR: erythrocyte sedimentation rate; RF: rheumatoid factor; CRP: C-reaction protein; CK: creatine kinase; Cr: creatinine; anti-dsDNA: anti-double-stranded DNA antibodies; AnuA: anti-nucleosome antibodies; anti-SSA: anti-SSA antibody; anti-SSB: anti-SSB antibody; anti-RNP Abs: anti ribonucleoprotein (RNP) antibodies; ANA: anti-nuclear antibodies; SLEDAI-2K: systemic lupus erythematosus disease activity index 2000.