Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus

Table 2

Correlation of serum anti-GAPDH antibodies with clinical and laboratory features of SLE patients.

Clinical manifestations and laboratory features	Anti-GAPDH
	Spearman
Age	0.207	0.018
WBC	-0.048	0.588
HB	-0.134	0.130
PLT	-0.083	0.349
IgG	0.282	0.001
IgA	0.119	0.179
IgM	0.177	0.045
Anti-dsDNA	0.091	0.308
C3	0.063	0.481
C4	-0.041	0.646
ESR	0.317	<0.001
CRP	0.132	0.137
RF	0.137	0.125
β2-GI	0.065	0.487
24 h proteinuria	-0.074	0.443
SLEDAI-2K	0.209	0.017

WBC: white blood cell; HB: hemoglobin; PLT: platelet count; IgG: immunoglobulin G; IgA: immunoglobulin A; IgM: immunoglobulin M; anti-dsDNA: anti-double stranded DNA antibodies; C3: complement component 3; C4: complement component 4; ESR: erythrocyte sedimentation rate; RF: rheumatoid factor; β2-GPI: anti-β2 glycoprotein I Abs; SLEDAI-2K: systemic lupus erythematosus disease activity index 2000.