Kidney Transplant Outcome Is Associated with Regulatory T Cell Population and Gene Expression Early after Transplantation

Table 4

Regulatory T cell absolute and related counts in examined groups of recipients in relation to controls and hemodialysed patients.

Cells	Control group	Dialysis group	value dialysis vs. control	Time from KTx	Mean ± SD (median; IQR)	value KTx vs. control	value KTx vs. dialysis
Treg/μl	(54.5; 41.7–71.8)	(57.8; 40.5–90.5)	0.745	1 w.	(28.5; 14.8–36.8)	<0.001	<0.001
				1 m.	(47.0; 30.4–70.6)	0.303	0.174
				3 m.	(44.1; 34.7–56.5)	0.105	0.061
				6 m.	(40.8; 27.4–53.1)	0.033	0.036
				12 m.	(38.0; 26.0–48.2)	0.035	0.030
Treg %T	(4.5; 3.7–5.3)	(5.3; 4.2–6.7)	0.129	1 w.	(4.1; 3.2–4.9)	0.206	0.003
				1 m.	(3.8; 3.1–4.5)	0.077	<0.001
				3 m.	(3.2; 2.6–3.8)	0.002	<0.001
				6 m.	(2.6; 2.2–3.3)	<0.001	<0.001
				12 m.	(2.8; 2.1–3.3)	<0.001	<0.001
				y.	(2.5; 2.2–3.5)	<0.001	<0.001
Treg % T CD4	(7.4; 5.6–8.3)	(7.7; 6.6–9.3)	0.357	1 w.	(6.2; 4.8–7.1)	0.014	0.001
				1 m.	(5.3; 4.7–6.1)	0.002	<0.001
				3 m.	(5.2; 4.4–6.3)	0.001	<0.001
				6 m.	(4.7; 4.1–5.8)	<0.001	<0.001
				12 m.	(5.3; 4.2–6.3)	0.003	<0.001
				y.	(4.6; 3.5–5.9)	<0.001	<0.001