An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders

Table 9

2010 ACR/EULAR classification criteria for rheumatoid arthritis. A is required for the diagnosis of a patient with confirmed RA.

Joint involvement	Score (0-5)	Serology	Score (0-3)	Period of symptoms	Score (0-1)	Acute-phase reactants	Score (0-1)
1 large joint	0	Negative RF and negative ACPA	0	<6 weeks	0	Normal level of CRP and ESR	0
2–10 large joints	1	Strong positive RF or week positive ACPA	2	≥6 weeks	1	Abnormal level of CRP and ESR	1
1–3 small joints (with or without accounting large joints)	2	Strong positive RF or strong positive ACPA	3
4–10 small joints (with or without accounting large joints)	3
>10 joints (with minimum 1 small joint)	5