Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye

Table 3

Correlations between positive antibody status and dry eye measures.

		Anti-SSA	Anti-SSB	RF	ANA	Anti-SP1	Anti-CA6	Anti-PSP
Tear osmolarity	Rho	0.08	-0.06	0.05	0.03	-0.01	-0.08	0.05
	value	0.39	0.52	0.63	0.80	0.92	0.40	0.60
Schirmer test	Rho	0.06	-0.01	-0.12	0.03	0.13	-0.06	-0.08
	value	0.62	0.91	0.30	0.83	0.26	0.62	0.49
Corneal staining	Rho	0.18	0.22	0.27	0.28	-0.10	0.21	0.02
	value	0.04	0.01	<0.001	<0.001	0.26	0.02	0.79
Conjunctival staining	Rho	0.24	0.13	0.22	0.18	-0.09	0.19	-0.03
	value	0.01	0.15	0.01	0.04	0.31	0.03	0.72
Total OSS	Rho	0.25	0.20	0.29	0.27	-0.10	0.26	0.00
	value	0.01	0.02	<0.001	<0.001	0.29	<0.001	0.97

Spearman correlation coefficient (rho) was used to analyze the associations between variables. Bolded values represent . SSA: Sjögren’s syndrome-related antigen A; SSB: Sjögren’s syndrome-related antigen B; RF: rheumatoid factor; ANA: antinuclear antibody; SP1: salivary protein 1; CA6: carbonic anhydrase 6; PSP: parotid secretory antigen; OSS: ocular staining score.