Chlorogenic Acid Inhibits BAFF Expression in Collagen-Induced Arthritis and Human Synoviocyte MH7A Cells by Modulating the Activation of the NF-κB Signaling Pathway

Figure 3

Effects of CGA on MH7A cell viability and apoptosis. (a) MH7A cells were treated with different concentrations of CGA (0, 20, 50, 80, and 100 μM) for 24 h; the viability was determined by CCK-8 assay. (b) CGA-induced apoptosis of MH7A cells stimulated with TNF-α. Annexin V-PI-stained cells were observed using a flow cytometer after 24 h incubation. Histograms showed the statistical analysis for the ratio of apoptotic cells. Values are presented as the (). vs. DMSO and vs. CGA 50 μM+TNF-α treated.

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