Research Article
Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome
Table 2
Allele and genotype frequencies of the CD40 rs1883832, rs4810485, and rs11086998 in the ACS and CG.
| | ACS
(%) | CG
(%) | OR (CI 95%) | |
| | rs1883832 | | | | | | Genotype | | | | | | C/C | 188 (58.8) | 194 (64.7) | 1 | — | | C/T | 121 (37.8) | 95 (31.7) | 1.31 (0.94-1.84) | 0.10 | | T/T | 11 (3.4) | 11 (3.6) | 1.03 (0.44-2.44) | 0.94 | | Allele | | | | | | C | 497 (77.7) | 483 (80.5) | 1.19 (0.90-1.56) | 0.22 | | T | 143 (22.3) | 117 (19.5) |
| | rs4810485 | | | | | | Genotype | | | | | | G/G | 186 (58.1) | 173 (57.6) | 1 | — | | G/T | 118 (36.9) | 113 (37.7) | 0.97 (0.70-1.35) | 0.86 | | T/T | 16 (5) | 14 (4.7) | 1.06 (0.50-2.24) | 0.87 | | Allele | | | | | | G | 490 (76.6) | 459 (76.5) | 0.99 (0.77-1.30) | 0.97 | | T | 150 (23.4) | 141 (23.5) |
| | rs11086998 | | | | | | Genotype | | | | | | C/C | 268 (83.8) | 242 (80.7) | 1 | - | | C/G | 47 (14.7) | 52 (17.3) | 0.82 (0.53-1.26) | 0.36 | | G/G | 5 (1.5) | 6 (2) | 0.75 (0.23-2.50) | 0.64 | | Allele | | | | | | C | 583 (91) | 536 (89.3) | 0.82 (0.56-1.19) | 0.29 | | G | 57 (09) | 64 (10.7) |
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ACS: acute coronary syndrome; CG: control group; CI: confidence interval; OR: odds ratio.
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