Relationship between the Degrees of Itch and Serum Lipocalin-2 Levels in Patients with Psoriasis

Figure 7

Therapeutic change of VAS and serum LCN2 levels between pre- and postbiologic treatment in the patients who have improvement in itch. (a) VAS was significantly lower in psoriasis patients with itch after treatment than before treatment. (b) Serum LCN2 levels were significantly lower in psoriasis patients with itch after treatment than before treatment (). (c) There was a tendency that serum LCN2 levels were lower in psoriasis patients without itch after biologic treatment. However, this trend did not reach statistical significance (). Bar graphs indicate of serum LCN2 levels. Significant differences were assessed by Student’s -tests: .

(a)

(b)

(c)