Research Article
DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma
Table 1
Correlations of DKK2 with clinical characteristics in PDAC patients.
| Characteristics | Total | DKK2 expression | value ( test) | High () | Low () |
| Age (years) | | | | 0.55 | <60 | 67 | 42 | 25 | | ≥60 | 141 | 93 | 48 | | Gender | | | | 0.579 | Male | 120 | 76 | 44 | | Female | 88 | 59 | 29 | | Tumor location | | | | 0.582 | Head | 139 | 92 | 47 | | Body/tail | 69 | 43 | 26 | | Size | | | | 0.92 | ≤2 cm | 25 | 16 | 9 | | >2 cm | 183 | 119 | 64 | | Tumor differentiation | | | | 0.012 | Well | 11 | 11 | 0 | | Moderate/poor | 197 | 124 | 73 | | T classification | | | | 0.876 | T1 | 3 | 2 | 1 | | T2 | 24 | 16 | 8 | | T3 | 141 | 89 | 52 | | T4 | 40 | 28 | 12 | | N classification | | | | 0.779 | Absent | 145 | 95 | 50 | | Present | 63 | 40 | 23 | | AJCC stage | | | | 0.88 | Stage I | 22 | 14 | 8 | | Stage II | 141 | 90 | 51 | | Stage III | 33 | 22 | 11 | | Stage IV | 12 | 9 | 3 | | Liver metastasis | | | | 0.348 | Absent | 195 | 125 | 70 | | Present | 13 | 10 | 3 | | Vascular invasion | | | | 0.177 | Absent | 180 | 120 | 60 | | Present | 28 | 15 | 13 | | Vital status | | | | 0.229 | Dead | 180 | 114 | 66 | | Alive | 28 | 21 | 7 | |
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