Journal of Immunology Research / 2019 / Article / Fig 1

Review Article

Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses

Figure 1

Interferon induction in normal and HIV-infected cells. (a) Interferon induces the induction of interferon-stimulated genes (ISG) through the activation of ISGF3. (b) HIV Vif leads to the degradation of STAT1 and Vpu, and Nef blocks phosphorylation of STAT1.

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