Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses

<div>Interferon induction in normal and HIV-infected cells. (a) Interferon induces the induction of interferon-stimulated genes (ISG) through the activation of ISGF3. (b) HIV Vif leads to the degradation of STAT1 and Vpu, and Nef blocks phosphorylation of STAT1.</div>

Journal of Immunology Research

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Figure 1

Figure 1: Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses 