Skin-Resident γδ T Cells Exhibit Site-Specific Morphology and Activation States

Figure 3

Morphological assessment reveals a significant variability in numbers of processes and size of γδ T cells across three tissue sites. (a) Cell length, measured as the greatest distance between two branches, was measured in γδ T cells in the ear, back, and footpad. As evidenced by their rounder morphology, cells in the footpad were significantly smaller in length than those in the ear or back. (b) The number of processes emanating from the cell body was counted in γδ T cells in the ear, back, and footpad. Cells in the ear and back have a significantly greater number of processes than γδ T cells in the footpad. Bar graphs represent mean ± SEM (, one-way ANOVA with post-hoc Tukey test;  = 3-5/group with ≥116 cells analyzed per site).

(a)

(b)