Ovarian Cancer Stem Cells with High ROR1 Expression Serve as a New Prophylactic Vaccine for Ovarian Cancer

Figure 1

Evaluation of CSC vaccination evoking antitumor efficacy in a mouse model. (a, b) Tumor size images on day 45 from the HO8910 tumor-bearing nude mice or on day 80 from the ID8 tumor-bearing mice after mice were initially vaccinated s.c. with different inactivated vaccines three times with a 10-day interval, followed by a challenge with HO8910 or ID8 cells at one week after final vaccination. (c, d) Kinetic quantification of tumor sizes by measuring two perpendicular tumor diameters using calipers. (e, f) Tumor-free mice. All the data represent the ( per group; representative images). Statistically significant differences between the experiment group and the normal group were indicated.

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