Ovarian Cancer Stem Cells with High ROR1 Expression Serve as a New Prophylactic Vaccine for Ovarian Cancer

Figure 3

Detection of the cytolytic activities of NK, CDC, and ADCC in the vaccinated mice. The NK cytotoxic activity (target cells: YAC-1) was analyzed by FCM in the HO8910 CSC vaccine-immunized mice (a) and the ID8 sphere vaccine-immunized mice (c). (b, f) Quantification of NK cytotoxic activity. (d) The splenocyte cytotoxicity (target cells: ID8) was analyzed by FCM in the ID8 sphere vaccine-immunized mice. (g) Quantification of the splenocyte cytotoxicity. (e) FCM analysis of the CDC activity. (h) Quantification of CDC activity in ID8 vaccines. (i) FCM analysis of the CDC activity in the HO8910 CSC vaccine-immunized mice. (j) Quantification of CDC activity in HO8910 vaccines. (k) FCM analysis of the ADCC activity. (l) Quantification of ADCC activity in ID8 vaccines. All the data represent the (). Statistically significant differences between the different groups were indicated.

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