Review Article

Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies

Table 3

Demographic and descriptive data of AIH patients treated at our institution between 10/2011 and 05/2016.

Demographic data
 Total number 10/2011-05/2016
 Age (median)50 years
 Male (42%)
 Female (58%)
 Cirrhosis (11%)
 Ascites (8%)
 Hepatic encephalopathy (grade 1) (3%)
 MELD, median (range)16 (6-23)
 Other autoimmune disease (55%)
Simplified AIH score (available for )
 Definite AIH () (27%)
 Probable AIH () (31%)
 No AIH () (42%)
Liver histology (available for )
 AIH typical (29%), interface hepatitis (11%)
 Inconclusive (25%)
 Not performed (36%)
Immunosuppressive therapy
 Prednisolone (mg), median (range)60 mg (50-100 mg)
 Prednisolone therapy duration (days), median (range)180 days (60-1080 days)
 Azathioprine (mg), median (range)100 mg (50-200 mg)
 Azathioprine start after weeks, median (range)3 weeks (1-12 weeks)
 Azathioprine intolerance (29%)
  Conversion to MMF (29%)
  Conversion to Everolimus (5%)
Outcome
 Survival (100%)
 Infection (3%)
 Liver transplantation (0%)