Expression and Significance of Immune Checkpoints in Clear Cell Carcinoma of the Uterine Cervix

Table 4

Expression of PD-L1, B7-H3, B7-H4, and VISTA in clear cell carcinoma and squamous cell carcinoma of the uterine cervix.

Variables	CCC ()	SCC ()	value
	B7-H3				<0.001
Positive	8	69
Negative	42	31
B7-H4			0.612
Positive	16	28
Negative	34	72
PD-L1			<0.001
Positive	11	91
Negative	39	9
VISTA in TCs			<0.001
Positive	0	23
Negative	50	77
VISTA in TAICs			<0.001
Positive	17	74
Negative	33	26

PD-L1: programmed cell death-ligand 1; VISTA: V-domain Ig suppressor of T cell activation; CCC: clear cell carcinoma; SCC: squamous cell carcinoma; TCs: tumour cells; TAICs: tumour-associated immune cells.