Research Article

Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage

Figure 2

Changed expression profiles of lncRNAs and mRNAs during CpG ODN-induced macrophage activation. (a) The heat map of all lncRNA expression at different time points during CpG ODN-induced macrophage activation from microarray data. (b) Scatter plots showing differentially expressed lncRNAs between macrophages with the stimulation with CpG ODN at 0 h and activated macrophages at different time points (4 h, 8 h, and 16 h). (c) Often differentially expressed lncRNAs between macrophages with the stimulation with CpG ODN at 0 h and activated macrophages at different time points (4 h, 8 h, and 16 h). (d) Hierarchical clustering showing often upregulated and downregulated lncRNAs among the four groups (macrophages stimulated for 0 h, 4 h, 8 h, and 16 h). (e) The heat map of all mRNA expression at different time points during CpG ODN-induced macrophage activation from microarray data. (f) Scatter plots showing differentially expressed mRNAs between macrophages with the stimulation with CpG ODN at 0 h and activated macrophages at different time points (4 h, 8 h, and 16 h). (g) Often differentially expressed mRNAs between macrophages with the stimulation with CpG ODN at 0 h and activated macrophages at different time points (4 h, 8 h, and 16 h). (h) Hierarchical clustering showing often up- and downregulated mRNAs among the four groups (macrophages stimulated for 0 h, 4 h, 8 h, and 16 h).