M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin <i>β</i>3, Focal Adhesion Kinase, and Cofilin

<div>Cell viability of AGS cells and THP-1 cells treated with 5FU. AGS cells and THP-1 cells were cultured in RPMI media and incubated for 24 h at 37°C. After 24 h of incubation, cells were treated with various concentrations of 5FU and incubated for further 24 h. After treatment, the media in the plate were removed and replaced with fresh media, and then 10 <i>μ</i>l of WST-1 solution was added in each well, and the plate was incubated for further 4 h at 37°C. Absorbance was obtained using the ELISA microplate reader at 490 nm wavelength. 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Journal of Immunology Research

fig2

Figure 2

Figure 2: M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin <i>β</i>3, Focal Adhesion Kinase, and Cofilin 

Figure 2 | M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin β3, Focal Adhesion Kinase, and Cofilin 